Using our algorithmic platform for epigenetic examination (APEX), Elysium calculates your biological age by examining more than 100,000 sites on your DNA where methylation has taken place—a biochemical process that does not change the inherent structure, but affects how your genes are expressed. 

We employ the custom Elysium chip, designed with biotechnology leader Illumina, to analyze your methylation patterns via a computational approach that significantly improves upon past biological clocks:

• The most precise epigenetic biological age test
  When you take a biological age test, you want to know that the result is as precise as possible and that it was developed with you, as an individual, in mind. In building Index, we made sure that a saliva sample run more than once would return near identical results each time. With other less precise clocks, your biological age might differ by a lot—by as much as 25 years!—Index ensures very minimal variability (~1 year), both thanks to the superior technology of APEX and the extensive validation of the test performed by our science team. When compared to five other epigenetic clocks, Index provides the most precise and reliable measure of biological age.
• Equivalent or better prediction of physical functioning status

  Index is more predictive of physical functioning status than a prior leading measure known as DNAmPhenoAge. This means biological age as measured by Index corresponds closely with measures of physical fitness and is a more accurate predictor of biological age.
• Better ability to track lifestyle changes over time
  Want to be able to track the results of a lifestyle intervention over time on your rate of aging? You need to eliminate noise over time. Repeatability and better prediction of physical functioning status add up to a better ability to track changes.

Approximately 6 weeks after receiving your saliva sample, we’ll send an email letting you know your results are ready. Before that, a lot happens behind the scenes.

• Week 1 to 2: Extracting DNA
  We extract your DNA and read sites across your genome where methylation, a type of epigenetic change, has occurred using a process called bisulfite conversion.
• Week 3: Profiling Methylation
  Your DNA gets loaded onto a chip and scanned to create your methylation profiles. Quality control ensures your data is robust and complete.
• Week 4 to 5: Calculating Biological Age

  We analyze sites of methylation across your genome to calculate your biological age.
• Week 6+: Tracking Your Progress
  
Use your report results and recommendations to see if making healthy changes can impact how you age.