Science has enabled us to focus on the cellular level to achieve optimal health, beyond what can be accomplished with diet and exercise. Basis is designed to optimize NAD+ levels and sirtuin function in our cells to support our most critical metabolic processes like cellular detoxification, DNA repair and energy production.
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Basis exemplifies Elysium’s focus on providing direct access
to scientific breakthroughs in health.
For decades, scientists have been searching for answers to what internal mechanisms lead to ongoing health as well as health decline. This led to the discovery of a critical coenzyme called NAD+, which controls cellular communication, and sirtuin proteins, which play a key role in our long-term health. Sirtuin proteins require NAD+ to function, and our NAD+ levels naturally decline over time, leading to a decline in cellular health. With a focus on NAD+ and sirtuins, we can help to sustain their function over time and support the health of the building blocks of our body -- our cells. This is the purpose of Basis.
Basis contains two novel compounds that support
the production of NAD+ and the activation of sirtuins.
"NAD is one of the most compelling bits of chemistry related to aging. Its presence in the body is directly correlated with the passage of time."FAST COMPANY, 2015
The most direct precursor to NAD+. It is the most readily usable and effective building block for creating more NAD+ inside the cell. NAD+ plays a crucial role in regulating core metabolic functions including cell function, DNA repair and energy production. NAD+ supplies decline naturally with age, thus reducing a cell’s ability to function optimally and potentially impacting baseline health.
A powerful antioxidant created by plants to protect against internal and external stresses, such as disease and the sun. It is closely related to resveratrol, a compound found in grapes and red wine, but more bioavailable, or easier, for the body to incorporate. Research has shown that pterostilbene, like NAD+, stimulates enzymes called sirtuins. They relate to critical cellular processes, from aging to circadian clocks to energy production.
Learn more about Basis, designed for long-term use
in adults from our 20s onward.
|Instructions||Take two capsules every morning with or without food. Each jar contains a 30-day supply.|
|Lead Scientist||Dr. Lenny Guarente, Elysium Co-Founder, Leads Science of Aging Lab at MIT.|
|Purity Assessment||Basis undergoes rigorous third party testing to confirm its content accurately reflects the ingredients listed on our label. Two capsules of Basis in our current lot contain 115% of promised quantity of NR, 112% of promised quantity of Pterostilbene.|
|Analysis||Through our established laboratory model, Basis meets standard measures of safety and tolerability.Both primary ingredients in Basis are GRAS (generally recognized as safe) under intended conditions of use by qualified experts.|
|Feedback||Subtle changes in overall feeling of well-being, sleep quality, energy consistency, cognitive function, and skin health are often reported within 4-16 weeks of starting. Note that cellular health may not always manifest results at the surface.|
|Dietary||Basis is vegetarian, vegan, gluten-free, nut-free, and contains no artificial colors or flavors. See ingredient information here.|
|Production||Basis is created in the United States in adherence with the FDA’s Good Manufacturing Practices.|
Review the scientific research that led to Basis and how it can impact our cellular health.
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Elysium has been featured in prominent publications that have lent their perspective on our mission and first product.
Cellular Detoxification is a core function of the body.
Exposure to everyday stresses and toxic elements damages cells.
Basis is designed to activate sirtuins and supplement the body’s NAD+ supply. Sirtuins and NAD+ contribute to the mechanisms that protect cells in stressful and toxic environments.
DNA Repair is a core function of the body.
The efficiency of our DNA repair systems, which protect our biological and genetic information, decreases over time, leading to an increased likelihood of mutations and health complications.
Basis works to activate sirtuins and supplement the body’s NAD+ supply. DNA repair is an NAD+ dependent process, and research has shown that DNA repairs faster and more efficiently in an environment with greater levels of NAD+.
Sleep is a core function of the body.
Without sufficient sleep, the brain is unable to rid itself of toxic free radicals produced during the day. Sleep impacts concentration, memory, and fat-burning systems that regulate weight.
Basis is designed to support a healthy sleep cycle by optimizing levels of NAD+, which supports circadian rhythm maintenance. Additionally, the mitochondrial sirtuin, SIRT3, which is NAD+-dependent, protects certain neurons of the brain against damage due to insufficient sleep.
At the surface, Basis can promote deeper, more restful sleep.
A protein's function is determined by its shape. Proper protein folding ensures proteins develop the correct functional shape to perform their designated tasks.
Proteins perform a range of vital tasks, from structural tasks such as enabling the body to move, to transporting molecules and catalyzing metabolic reactions. Protein homeostasis, or proteostasis, refers to the proper function of the cellular pathways that govern the production, folding, degradation of proteins. This process is essential and organismal survival and healthy aging. Dysfunction in this area has been associated with protein aggregation and age-related degenerative diseases. Both NAD+ and sirtuins are linked closely to cellular proteostasis, as SIRT1 activates mitochondrial biogenesis via NAD+.
Energy production is a core function of the body, important to all metabolic processes.
Energy originates in our cells within our mitochondria, which are responsible for cellular respiration and ATP production. The number and function of mitochondria decreases over time, impacting the body’s ability to produce energy.
Optimizing NAD+ supply supports the production of ATP, the chemical energy in cells, and improves the efficiency of existing mitochondria. NAD+ also helps to form mitochondria, fueling SIRT1, which regulates processes to produce new mitochondria.
At the surface, Basis can promote more consistent, stable energy throughout the day.
Cognition is a core function of the body, enabling us to acquire and retain knowledge.
As we age, cognitive function declines impacting memory, clarity of thought, reasoning and decision making.
Basis works to activate the sirtuin SIRT1, which has been shown to promote memory function. This activation strengthens synapses based on activity patterns and allows for increased signal transmission. Basis provides a deterrent against degeneration of the brain’s neurons.
At the surface, Basis can promote sharper cognitive function.
LOT NUMBER: 0141-6140
Find your lot number on the bottom of your Basis jar. If different than current lot, simply contact us at email@example.com for information on your lot.