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Your Immune System Naturally Declines Over Time
Your immune system provides a powerful defense against stressors in everyday life. As you age, it declines and becomes less efficient. Science has now identified a factor that contributes: the accumulation of senescent cells. These are cells throughout the body that stop dividing in response to cellular stressors and instead linger, secreting problematic molecules that can impact neighboring normal cells. Everyone has senescent cells, but as we age, our bodies struggle to clear senescent cells and they build up—including in the immune system.
Senescent immune cells can also impact other tissues as they circulate throughout our body. Recent research in mice suggests that they can even accelerate systemic aging.*
*There’s no evidence to date that this animal study can be extrapolated to humans.
Target Immune Aging With Senolytics
There is a solution to the age-related buildup of senescent cells: a class of compounds called senolytics. When taken intermittently, senolytics help clear senescent cells and support healthy immune function. Format’s Senolytic Complex contains fisetin and quercetin, two extensively researched flavonoids found in fruits and vegetables with potent senolytic activity. Chinese ginseng and chestnut rose extracts further support senolytic activity, and have also been shown to reduce senescent cell burden triggered by strenuous exercise.See the Science
“Format is unique in combining a daily immunomodulatory cocktail with intermittent, proven senolytic compounds to clear senescent cells. It is a safe way to provide multi-pronged immune support that is not available in any other health supplement.”
Leonard Guarente, Ph.D., Elysium Co-founder and Chief Scientist
A Powerful Combination for Immune Support
Format also provides a once-daily immune supplement with potent ingredients to support the innate and adaptive immune systems. These include the foundational micronutrients vitamin C, zinc, and selenium, as well as other natural compounds that offer advanced protection against free radicals and oxidative stress, and promote cellular renewal and intracellular recycling by activating autophagy.
Format your immune system for the 21st century.Starting from $40/mo
Format 101: The Science
Did You Know You Have Two Types of Immune Systems?
The immune system consists of two main components—the innate and adaptive immune systems. Think of the innate immune system as the first line of defense—it is nonspecific, and responds in the same way to all pathogens. In contrast to the fast-acting innate immune system, the adaptive immune system takes longer (days to weeks) and is highly targeted.
What is Autophagy?
Autophagy is a process where damaged and defective cells are removed and recycled so healthy new ones can be built. This “cellular housekeeping” is crucial for immune health and combating immune aging.