A collection of terms commonly used in aging research.

Sirtuins are a family of seven proteins that play an essential role in our health—from DNA maintenance to mitochondrial biogenesis and cellular energy production. This article explains the science of sirtuins with a focus on two of its members, SIRT1 and SIRT3.

Learn what to consider when choosing an NMN supplement with this guide: From dosage and delivery method to quality and purity.

System ages represent the biological age of individual systems–including brain, heart, metabolic, and immune–and provide a snapshot of their relative contribution to your overall long-term health and wellness. Learn how we measure them and what they mean to you.

While scientific research once supported the health benefits of moderate drinking, recent studies have made a case for abstinence. One study found that even one drink per day was associated with reduced global brain volume and two years of brain aging for an average 50-year-old.

The holiday season is one of the most joyful times of the year—and it brings with it the challenge of staying healthy and well-resourced. Here’s a list of easy-to-implement, science-based tips to help you keep your health while you celebrate and into the new year.

NMN or nicotinamide mononucleotide is a safe and efficient precursor to NAD+, the essential coenzyme and key metabolite found in every cell of the human body, and involved in over 500 different cellular reactions. Read on to explore what NMN is, how our bodies turn NMN into NAD+, and the benefits of NMN supplementation.

NR is a highly efficient precursor to NAD+, but its cousin molecule NMN is raising eyebrows as the new kid on the block.

Our DNA makes us who we are, but it’s epigenetics that brings our story to life. Here’s the science of epigenetics, including how it works and how it relates to biological clocks.

NAD+ IV therapy is offered widely at addiction clinics and IV “drip” bars and wellness centers. We examined the research and asked an NAD+ expert to see if there’s evidence to support the claims.

There are differences between the two most popular NAD+ precursors. Learn the distinctions and what supplementing with each—or both—of them can do for you.

Our body contains trillions of tiny organelles called mitochondria. Mitochondrial function is essential for metabolic health, cellular energy creation, and so much more – here’s why.

Energy homeostasis is a biological process by which our cells balance energy production and expenditure. Maintaining energy balance is critical for the survival and proper functioning of our cells. As we age, this balance becomes dysregulated. 

Intermittent fasting is a catch-all term that refers to several eating schedules or patterns with periods of time when you don’t eat or when you reduce the number of calories you’re taking in.

Metabolism is the sum of every chemical reaction in your body and is influenced by a variety of factors, including age, genes, stress levels, sleep, and exercise. Learn how it works and science-based tips to support it. 

The idea of “boosting” your immune system is an understandably appealing concept—who wouldn’t want a supercharged immune system that goes above and beyond to keep you healthy? The reality, however, is a bit more complex.

The Hayflick Limit suggests that a normal human cell can replicate and divide roughly fifty times before it cannot divide anymore. With cellular senescence, the cell loses the ability to multiply before it reaches that limit.

Autophagy is a process where our cells remove components that are no longer functional or necessary and recycle them to build healthy new ones. This “cellular housekeeping” is crucial for immune health and the body’s ability to respond to immune aging.

The immune system consists of two main components—the innate and adaptive immune systems. Think of the innate immune system as the first line of defense—it is nonspecific and responds in the same way to all pathogens. In contrast to the fast-acting innate immune system, the adaptive immune system takes longer (days to weeks) and is highly targeted.

Omega-3s are extremely important for health: they are necessary for functions from muscle activity to cell growth. They also happen to be one of the two essential fatty acids that aren’t made by the body, and so must be derived from diet. But what are your options if you just don’t get around to doing that?

Everyone knows that DNA is the code that makes you, well, you. But did you know that that code can be used by your body in different ways?

Like many other types of product, epigenetic clocks have varying degrees of accuracy. So how do you know which is the most precise predictor of your biological age?

Why does the label say “Supplement Facts” rather than “Nutrition Facts”? And who decides your recommended daily value of vitamins and minerals, anyway? This primer explains.

These molecules become NAD+ over a series of chemical transformations. Here’s what you need to know about each one.

These two forms of nicotinamide adenine dinucleotide are not exactly the same thing, but they’re chemically similar. It’s complicated. We'll explain.

You’ve heard of this vitamin, and you’ve maybe even taken it, but do you really know what it does? Or where it comes from? Here’s what you need to know.

If you zoom in on your body’s most fundamental activity, you’d see cells and molecules hard at work. You might be surprised to learn that some of the most vital players at work are ones you’ve never heard of.

Sirtuins help regulate your cellular health. Here’s what you need to know about how they work, what they can do for your body, and why they rely on NAD+ to function.

A cousin to resveratrol but more potent—pterostilbene is found in certain berries and nuts and serves as a powerful antioxidant.

Your body acts like an efficient factory to keep the coenzyme NAD+ active throughout your life. Here’s how it works and how you can help the body make more NAD+.

This form of Vitamin B could be the key to restoring NAD+ levels — here’s why.

How fast have you been aging? Let us explain.

NAD+ is essential to the creation of energy in the body and the regulation of pivotal cellular processes. Here’s why it’s so important, how it was discovered, and how you can get more of it.

You’ve probably heard that omega-3s are important for your health, but do you know why? Discover how they’re different from other fats, and how to make sure you're getting the right amount.

The legislation that governs dietary supplements is called DSHEA, and it enumerates nine different categories. This guide explains what they are and what they mean.

This important amino acid has been attracting attention in the science community for its role in overall health.