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As You Age, Your Metabolism Becomes Dysregulated and Less Efficient
Metabolism is the sum of the reactions in your cells that convert food into the energy you need for life. As you age, your metabolism becomes dysregulated and less efficient, and this affects the way your cells function.
This happens for two main reasons: First, you have less of a coenzyme central to hundreds of metabolic processes called NAD+, which especially affects the crucial reactions inside your mitochondria. Second, NAD-dependent enzymes that help facilitate those reactions inside the mitochondria, like the protein called SIRT3, slow down.
Boosting NAD+ with NMN to Target Metabolic Aging
NAD+—a coenzyme, or helper molecule that makes metabolic reactions possible—assists your cells in making energy through glycolysis, the TCA cycle, and the electron transport chain. NAD+ levels drop as you get older, and these activities diminish. Signal provides NMN, one of the most efficient precursors of NAD+.
Early human and preclinical evidence suggests that NMN has different benefits from other NAD+ precursors, including tissue preference and function. Combining different NAD+ precursors such as those found in Signal and Basis may help ensure that NAD+ levels are elevated across a broader range of tissues and provide a more comprehensive approach for NAD+ supplementation.
See the Science
“Signal is a novel, mitochondria-centric product formulated to counter aging-dependent declines in metabolism by promoting youthful energetics and metabolic efficiency.”
Leonard Guarente, Ph.D., Elysium founder, chief scientist, and renowned aging researcher and professor
Activating SIRT3 to Support Mitochondrial Health
What happens inside your mitochondria—your cellular powerhouses—is crucial. All your metabolic processes occur here, from energy production and synthesis of cellular building blocks to waste management. The mitochondrial protein SIRT3 drives many of these reactions, as well as protects and generates new mitochondria. The natural ingredients in Signal’s SIRT3 Metabolic Activation Complex, honokiol and viniferin, are designed to work synergistically with NMN to activate SIRT3 to promote mitochondrial health and synthesis, which in turn support metabolic health.
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ALT As You Age, Your Metabolism Becomes Dysregulated and Less Efficient
Metabolism is the sum of the reactions in your cells that convert food into the energy you need for life. As you age, your metabolism becomes dysregulated and less efficient, and this affects the way your cells function.
This happens for two main reasons: First, you have less of a coenzyme central to hundreds of metabolic processes called NAD+, which especially affects the crucial reactions inside your mitochondria. Second, NAD-dependent enzymes that help facilitate those reactions inside the mitochondria, like the protein called SIRT3, slow down.
ALT Boosting NAD+ with NMN to Target Metabolic Aging
NAD+—a coenzyme, or helper molecule that makes metabolic reactions possible—assists your cells in making energy through glycolysis, the TCA cycle, and the electron transport chain. NAD+ levels drop as you get older, and these activities diminish. Signal provides NMN, one of the most efficient precursors of NAD+.
Early human and preclinical evidence suggests that NMN has different benefits from other NAD+ precursors, including tissue preference and function. Combining different NAD+ precursors such as those found in Signal and Basis may help ensure that NAD+ levels are elevated across a broader range of tissues and provide a more comprehensive approach for NAD+ supplementation.
See the Science
“Signal is a novel, mitochondria-centric product formulated to counter aging-dependent declines in metabolism by promoting youthful energetics and metabolic efficiency.”
Leonard Guarente, Ph.D., Elysium founder, chief scientist, and renowned aging researcher and professor
ALT Activating SIRT3 to Support Mitochondrial Health
What happens inside your mitochondria—your cellular powerhouses—is crucial. All your metabolic processes occur here, from energy production and synthesis of cellular building blocks to waste management. The mitochondrial protein SIRT3 drives many of these reactions, as well as protects and generates new mitochondria. The natural ingredients in Signal’s SIRT3 Metabolic Activation Complex, honokiol and viniferin, are designed to work synergistically with NMN to activate SIRT3 to promote mitochondrial health and synthesis, which in turn support metabolic health.