The Key Components of Basis: What do they do and how in the world do you pronounce them?

Nicotinamide riboside and pterostilbene. They are the two key compounds in BASIS, Elysium Health’s dietary supplement that targets fundamental cellular systems such as those associated with DNA repair, energy production and protein function.

But can you pronounce them? And do you know what they really do?

Maybe not, but we think everyone should.

Let’s start with the easier task: Understanding what, exactly, nicotinamide riboside and pterostilbene are, and what decades of scientific research have taught us about how they function.

First, we have nicotinamide riboside, commonly referred to as NR, and which has been shown to increase levels of an important, naturally occurring coenzyme called NAD+. After decades of rigorous scientific study of NAD+, scientists have learned that it plays a crucial role in regulating core metabolic functions, including cell function, inflammation, DNA repair and energy production. Research has also shown that NAD+ declines naturally with age, thus reducing a cell’s ability to function optimally and potentially impacting baseline health. Much of the research on NAD+ has focused on understanding how maintaining sufficient levels of NAD+ can potentially have a positive impact on the aging process as well as age-related diseases such as Alzheimer’s.

Next we have pterostilbene, an antioxidant created by plants to protect against both internal and external stresses, such as disease and the sun. It is closely related to resveratrol, a compound found in grapes and red wine, but appears to be more bioavailable. Both pterostilbene and resveratrol are believed to have anti-inflammatory properties. (Inflammation is believed by scientists to play a role in an array of diseases, including cancer and stroke.) However, even more interesting is the fact that research has shown that pterostilbene, like NAD+, stimulates enzymes called sirtuins, which regulate an array of cellular processes, from aging to circadian clocks to energy production.

And now for the hard part: Say it five times fast!

Nicotinamide riboside (nick-a-TIN-a-mide RI-buh-side)
Pterostilbene (Taro-STILL-bene)
Sirtuins (SIR-two-ins)

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