Developed with the University of Oxford: The science behind Matter.


Elysium partnered with Oxford to develop a product for brain health during the aging process. Matter supports and maintains cognitive function and memory, and slows the brain atrophy that occurs as we get older.


Matter is founded on the findings of the VITACOG study, conducted at the University of Oxford in a cohort of older adults. The main outcome measure was the change in the rate of atrophy of the whole brain assessed by MRI scans following supplementation with a unique tri-vitamin complex.

Location Conducted at the University of Oxford
Participants 168 adults over 70 years of age with mild cognitive concerns, two-year clinical trial
Protocol Double-blind, placebo-controlled, randomized—the “gold standard” in studies
Results The B-vitamin complex supports brain health, significantly reducing age-related brain atrophy. Individual results may vary and not everyone may achieve results

Result: Slows Brain Atrophy

Over the course of two years, the B-vitamin complex in Matter measurably slowed the rate of brain atrophy by 30%, and in certain brain regions involved in visuospatial learning and spatial long-term memory, the rate of gray matter atrophy was slowed by an average of 86%.

Result: Supports Brain Function and Health

Even if you’re healthy, you lose up to 20% of your brain volume over your lifespan. In normal aging, this decline is sometimes linked to declining brain function, impacting memory or concentration. Over time, lifestyle factors like alcohol consumption, smoking, and poor sleep habits can accelerate gray matter decline. The results from Oxford’s VITACOG study provide cause and effect evidence demonstrating that the B-vitamin complex in Matter can play an important role in supporting normal brain structure and function, and long-term brain health.

Result: Regulates Homocysteine Metabolism

Among many reasons to keep homocysteine levels normal: high concentrations of this amino acid in your blood are associated with brain atrophy in healthy older adults. Science shows that B vitamins can effectively lower homocysteine levels.