Cellular Biology

Thermogenesis

/ˌTHərmōˈjenəsəs/

Derived from the Greek word thermos (or "heat"), thermogenesis is any metabolic process that generates heat. In mammals, thermogenesis is commonly used to describe the heat-producing process involved in defending core body temperature or burning excess calories (diet-induced thermogenesis). Brown adipose tissue (brown fat) is a significant source of thermogenesis and, when activated, increases energy expenditure. NAD+ metabolism is essential to this process and boosting NAD+ levels with precursors like NMN can help activate brown fat thermogenesis.