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Cofactor

Advanced Collagen System with NAD+ Boost

$75

per pouch

Purchase Options

Description

Youthful skin (plus, hair, nails, bones, and joints) requires collagen and NAD+. Unfortunately, both decline starting in our 20s. Cofactor by Elysium Health is an advanced 4-in-1 collagen system that combines: collagen peptides, nicotinamide riboside (NR), a precursor that’s clinically proven to boost NAD+, hyaluronic acid, and vitamin C.

  • Collagen peptides (grass fed) to stimulate and provide the building blocks for collagen production*
  • NAD+ booster NR to promote cellular youth for optimal collagen production*
  • Hyaluronic Acid to improve skin elasticity, hydration, and barrier function*
  • Vitamin C to support collagen production*
  • Reduce fine lines and wrinkles*
  • Bone, joint, hair, and nail support*

Ingredients

Cofactor is the advanced 4-in-1 collagen system that combines: 

  • 20 g collagen peptides from grass-fed bovine
  • 250 mg nicotinamide riboside chloride (NR), a clinically proven NAD+ booster.
  • 120 mg hyaluronic acid (HA)
  • 90 mg vitamin C
  • Cofactor is gluten-free, dairy-free, soy-free, sugar-free, non-GMO, and contains no artificial flavors or colors.
  • See nutrition label for more information.
  • The quality and purity information of every lot is available here.

Recommended Use

  • Combine 1 scoop with 8 fl oz of liquid and mix thoroughly. Scoop included.
  • Each pouch contains 28 daily servings. 
  • This product is intended for healthy adults. If pregnant or nursing, consult with your physician before using.
  • See Cofactor Recipes for delicious, Elysium-approved ways to take Cofactor.
View full details

Collagen production requires youthful cells

NAD+ is a critical coenzyme found in every cell in your body that helps keep cells youthful and functioning optimally. As we age, our NAD+ levels naturally decline. In skin, NAD+ levels decline by almost 60% between young adulthood and middle age, impacting collagen production—by age 40, we’ve lost about 25% of our collagen.

Cofactor provides an advanced 4-in-1 collagen system that combines: collagen peptides, which provide the stimulus and the building blocks for collagen; nicotinamide riboside, a clinically proven NAD+ booster, to help improve the health and function of the cells that use these building blocks to produce collagen; hyaluronic acid to improve skin hydration and elasticity; and vitamin C, an essential cofactor for collagen synthesis.

Illustration showing relationship between cellular aging and collagen decline in aging skin.

Better skin, hair, nails—and more

Human clinical studies demonstrate that supplementation with collagen peptides significantly increases skin elasticity and dermal density (a reflection of the amount of structural components like collagen and elastin in the dermis) and improves wrinkles, skin roughness, and cellulite scores. Collagen peptides have also been shown to support healthy hair and nail growth. Hyaluronic acid, another key ingredient in Cofactor, has been clinically proven to increase skin moisture levels, boost elasticity, and improve skin barrier function.

See the science

Supercharge your collagen system by combining Cofactor with Mosaic

Elysium’s skin aging and collagen support supplement, Mosaic, fights oxidative stress from sun exposure and aging—the main culprit in collagen loss. Combine Cofactor with Mosaic to supercharge your collagen system by protecting the collagen you’re replacing with Cofactor.

Bone and joint benefits for healthy mobility

As the most abundant protein throughout our bodies, collagen is the primary building block for the body’s connective tissues, such as bones, tendons, ligaments, and cartilage, playing a key role in supporting our strength, flexibility, and movement. Human clinical studies show that oral supplementation with collagen peptides improves markers of bone health, including bone mineral density (in postmenopausal women), and supports joint mobility and comfort.

Cofactor 101: The Science

Here's what happens when you take Cofactor, starting at 3 weeks.

Explore the benefits of Elysium’s advanced collagen support system, Cofactor, from three weeks to one year and beyond.

collagen fibers

What happens to collagen with age?

Collagen keeps your skin resilient, plump, and youthful. Learn why it changes with age and what you can do to slow its decline.

Cofactor recipes

Cofactor in the kitchen: serious science, simple recipes

Looking for delicious ways to incorporate Cofactor in your daily routine? Here are some of the Elysium team’s favorite ways to take Cofac...

Frequently Asked Questions

What is Cofactor and what does it do?

Cofactor is an advanced 4-in-1 collagen support system that combines: collagen peptides, which provide the stimulus and the building blocks for collagen; nicotinamide riboside, a clinically proven NAD+ booster, to help improve the health and function of the cells that use these building blocks to produce collagen; hyaluronic acid to improve skin hydration and elasticity; and vitamin C, essential for collagen synthesis.

Why does Cofactor contain nicotinamide riboside?

Youthful skin requires collagen and NAD+, which both decline starting in our 20s. NAD+ decline—a hallmark feature of aging, is associated with a decline in cellular health and function, resulting in reduced collagen production. Cofactor uniquely combines collagen peptides with nicotinamide riboside (NR), a precursor that’s clinically proven to boost NAD+, to create an optimal environment for sustained collagen production.

What does hyaluronic acid do?

Hyaluronic acid (HA) is a major component of the skin and plays a critical role in maintaining skin hydration. As we age, our skin produces less HA, contributing to decreased hydration, plumpness, and impaired barrier function. Clinical studies show that oral supplementation with HA increases whole-body skin moisture content throughout the layers of the skin, improves skin barrier function, and increases skin elasticity.

When should I expect to see benefits?

While individual results may vary, clinical studies suggest benefits starting around 3 weeks with increased skin hydration. Improvements in skin elasticity have been demonstrated at 2 months and a reduction in wrinkles and improvements in skin texture by 4 months. Hair and nail benefits have been reported at 6 months. This timeline may differ from the typical user’s experience and is not intended to represent or guarantee that every user will achieve the same or similar results.

How does Cofactor taste?

Cofactor is unflavored with minimal taste and aftertaste.

How do I take Cofactor?

We recommend dissolving Cofactor in liquids (like smoothies, protein shakes, juices, coffee or tea, or water) and foods (like yogurt, or overnight oats). Unlike conventional collagen supplements, Cofactor contains nicotinamide riboside, which is sensitive to prolonged exposure to high temperatures. Therefore, Cofactor dissolved in hot beverages should be consumed within 30 minutes. One serving a day is all you need.

Can I combine Cofactor with Basis or Signal?

Yes, you can combine Cofactor with Basis and/or Signal. Cofactor, Basis, and Signal each contain 250 mg of an NAD+ precursor. Clinical studies have demonstrated that daily supplementation with up to 2,000 mg of nicotinamide riboside (the NAD+ precursor in Cofactor and Basis) or 1,000 mg of nicotinamide mononucleotide (the NAD+ precursor in Signal) in healthy individuals is safe and well tolerated. Taking Basis and/or Signal can help support additional cellular processes not provided by ingredients in Cofactor—Basis contains pterostilbene (a SIRT1 activator) to support DNA maintenance, while Signal contains the SIRT3 Activation Complex, which supports mitochondrial health.

How do subscriptions work?

Our prepaid subscription plans are our most cost-effective options. When you select a prepaid annual plan, the pricing offers savings to customers who commit to a long-term subscription. Prepaid subscriptions are considered final sale, so if you cancel in the middle of a prepaid plan, you will continue to receive the remaining pouches, and the cancellation will take effect at the end of your plan before renewal. Our monthly subscriptions are $62/month and can be canceled at any time prior to your next shipment. You can also place a single-purchase order by selecting “Individual Purchase” on the checkout page for $75. Please contact our Customer Experience Team at care@elysiumhealth.com if you need to talk about your plan.

Where do you ship?

Cofactor, Vision, Index, and the Senolytic Complex are currently only available to ship and bill to addresses located in the U.S. Mosaic, Basis, Signal, Matter, and Format are available in the United States and Canada. Sign up for our newsletter here to be notified of updates related to the international availability of our products.

When will I receive my product?

From the time an order ships, our free standard shipping delivers in 5-7 business days. For an additional $25 fee, expedited shipping arrives in 2-3 business days. Please allow 1-2 business days to process your order.